The Miami Heat star is set to reach the milestone during Wednesday's game against the Golden State Warriors.
The 28-year-old power forward is 18 points away from the mark, which he's most likely to hit when the Heat takes on the Golden State Warriors.
So far, the title belongs to Los Angeles Lakers star Kobe Bryant, who scored his 20,000th point when he was 29 years old. Wilt Chamberlain and Michael Jordan also reached the milestone before they turned 30.
Kareem Abdul-Jabbar currently holds the NBA record on the all-time scoring list with 38,387 points, a feat James says he's not sure he wants to actively take on.
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